Lesser known mycobacteria.

Lesser known mycobacteria.

Lesser-known bunyavirus infections.

This paper reviews less well-known or less widely distributed viruses of the Bunyaviridae family that are nonetheless of significant veterinary and public health concern. These include: Cache Valley fever, Main Drain, Ingwavuma, Bhanja and Heartland viruses. A description of the agents, clinical signs of infection, epidemiology, and insect transmission is provided for each, and the authors disc...

Some lesser known Irish physicians.

THE Osler Club was founded to commemorate the name of one of the greatest and best-known physicians of all time, and it seemed fitting that at the Society's first meeting in Dublin the opening paper should try to pay tribute to some other physicians who, given the time, place and opportunity might have become just as well known, but were fated to work in relative obscurity, 'great' only in the ...

Retigabine: Lesser - Known Effects in Preclinical Studies

Retigabine is a novel anticonvulsant with unique mechanism of action. It induces hyperpolarization of the neuronal membrane by activating a specific type of potassium channels (Kv7, KCNQ). Retigabine is approved by EMA as “adjunctive treatment of partial onset seizures with or without secondary generalisation in adults aged 18 years and above with epilepsy”. The purpose of this review is to res...

Lesser-Known Molecules in Ovarian Carcinogenesis

Currently, the deciphering of the signaling pathways brings about new advances in the understanding of the pathogenic mechanism of ovarian carcinogenesis, which is based on the interaction of several molecules with different biochemical structure that, consequently, intervene in cell metabolism, through their role as regulators in proliferation, differentiation, and cell death. Given that the e...